Staff profile testing

Dr. Tony Mc Elligott

Dr. Tony Mc Elligott

Assistant Prof in Molecular Haematology, Haematology

Assistant Prof in Molecular Haematology

3531896 3387http://people.tcd.ie/mcelliga

Publications and Further Research Outputs

  • Laura Christine Kickham, Anthony M McElligott, Adriele Prina-Mello, Elisabeth A Vandenberghe, Yuri Volkov, Paul Browne, Interrogating the Interaction of CD52 Functionalised Metallic Nanoparticles with Malignant B Lymphocytes , Blood, 126 , (23 ), 2015Journal Article, 2015, URL
  • Ghnewa YG, O'Reilly VP, Vandenberghe E, Browne PV, McElligott AM, Doherty DG, Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8+ invariant natural killer T cells, Clinical Immunology, 183, 2017, p91 - 98Journal Article, 2017, URL
  • Bright S.A, Byrne A.J, Vandenberghe E, Browne P.V, McElligott A.M, Meegan M.J, Williams D.C, Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers, Oncology Reports, 41, (5), 2019, p3127 - 3136Journal Article, 2019, DOI , URL
  • Anthony M McElligott , Eamon P Breen , Ruth Cleary , Sarah Brophy, Fiona McCarthy , Emma Heffernan , Vincent O'Mahony , Nicola Gardiner , Derek G Doherty, Bridgette Byrne , Paul V Browne , Catherine M Flynn, , Characterisation of Naive Immunological Profile of Umbilical Cord Blood: The Role of Mucosal-Associated Invariant T Cells and Functional Defects of T Cells and Natural Killer Cells, Blood, American Society of Hematology, San Diego, CA, USA, 1-4 Dec, 2018, 130, (1), American Society of Hematology, 2017, pp3590-Poster, 2017, DOI
  • AM McElligott et al, Matrix metalloproteinase and tissue inhibitor of metalloproteinase regulation of the invasive potential of a metastatic renal cell line, Biochemical Society Transactions, 25, 1997, p147-Journal Article, 1997
  • Tissue Inhibitor of Metalloproteinase Expression in, editor(s)Walden P., Trefzer U., Sterry W., Farzaneh F., Zambon P. , Gene Therapy of Cancer. Advances in Experimental Medicine and Biology, Boston, MA, USA, Springer, 1998, pp73 - 77, [A. M. McElligot, tA. H. Baker, H. McGlynn]Book Chapter, 1998
  • Sarah Brophy , Fiona M Quinn, David O'Brien, Paul Browne, Elisabeth A. Vandenberghe , Anthony M. McElligott, The Regulation of STAT3 and Its Role in the Adhesion and Migration of Chronic Lymphocytic Leukaemia Cells, Blood, American Society of Hematology Annual Meeting, San Diego, CA, USA, 3-6, December, 201, 128, (22), American Society of Hematology, 2016, pp4347-Poster, 2016, URL
  • Brophy S et al, Microenvironmental-Mediated Regulation of L-Selectin in Chronic Lymphocytic Leukaemia, Blood, American Society of Hematology Annual Meeting, Orlando, FL, USA, 5-8 December, 2015, 126, (23), American Society of Hematology, 2015, pp4133 - 4133Poster, 2015, URL
  • Anthony M. McElligott, Elaina N. Maginn, Lisa M. Greene, Elizabeth Vandenberghe, Amjad Hayat, Margaret M. McGee, Giuseppe Campiani, Paul V. Browne, D. Clive Williams, Daniela M. Zisterer and Mark P. Lawler, Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic B-lymphoid malignancies, Cancer Research, 97th AACR Annual Meeting, Washington DC, USA, 1-5 April, 2006, 66, (8), AACR, 2006, pp899 - 899Poster, 2006, URL
  • Viola Previtali , Helene B Mihigo , Rebecca Amet, Anthony M McElligott , Daniela M Zisterer , Isabel Rozas , Exploring the Anti-Cancer Mechanism of Novel 3,4'-Substituted Diaryl Guanidinium Derivatives, Pharmaceuticals (Basel), 13, (12), 2020, p485Journal Article, 2020, DOI
  • Rebecca Amet, Viola Previtali, Helene Mihigo, Emily Sheridan, Sarah Brophy, Patrick J. Hayden, Paul V. Browne, Isabel Rozas, Daniela Zisterer, and Anthony M. McElligott., A Novel Aryl-Guanidinium Based Compound Targets the STAT3 Signalling Pathway, Downregulates MCL-1 Expression and Induces Anti-Myeloma Activity., Blood, American Society of Hematology, 4 -8 December 2020, 136, 2021Poster, 2021, DOI
  • Carmel Waldron,David O'Brien,Sarah Brophy,Kanthi Perera,Gerard M. Crotty,Eoghan Dunlea,Aileen Walsh,Michelle Connolly,Ruth Clifford,Hilary O'Leary,Ashique Khan,Greg Lee,Emer Atkinson,Giao Le,Alexander Gillett,Christopher L. Bacon,Anthony M. McElligott,Fiona Quinn,Elisabeth Vandenberghe, Epidemiology of chronic lymphocytic leukaemia in an Irish subpopulation with total case ascertainment: an additional tool for health economic planning, British Journal of Haematology, 2021Journal Article, 2021, DOI , URL , TARA - Full Text
  • Rebecca Amet, Viola Previtali, Helene B. Mihigo, Emily Sheridan, Sarah Brophy , Nadhim Kamil Hante, Maria Jose Santos-Martinez, Patrick J. Hayden, Paul V. Browne, Isabel Rozas, Anthony M. McElligott , Daniela M. Zisterer , A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma , Life Sciences, 290, 2022Journal Article, 2022, DOI , TARA - Full Text
  • McElligott, AM, Maginn, EN, Greene, LM, McGuckin, S, Hayat, A, Browne, PV, Butini, S, Campiani, G, Catherwood, MA, Vandenberghe, E, Williams, DC, Zisterer, DM, Lawler, M, The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia., Cancer Research, 69, (21), 2009, p8366 - 8375Journal Article, 2009, DOI
  • Verma, NK, Dempsey, E, Conroy, J, Olwell, P, McElligott, AM, Davies, AM, Kelleher, D, Butini, S, Campiani, G, Williams, DC, Zisterer, DM, Lawler, M, Volkov, Y, A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin., Journal of Molecular Medicine , 86, (4), 2008, p457- 469Journal Article, 2008, DOI , TARA - Full Text
  • Cunningham, O, McElligott, AM, Carroll, AM, Breen, E, Reguenga, C, Oliveira, ME, Azevedo, JE, Porter, RK, Selective detection of UCP 3 expression in skeletal muscle: effect of thyroid status and temperature acclimation., Biochimica et biophysica acta, 1604, (3), 2003Journal Article, 2003
  • Reid, HM, McElligott, AM, McGlynn, H, Phenotypic alterations in Caki-1 cells as a consequence of TIMP-1 overexpression., Cancer letters, 169, (2), 2001Journal Article, 2001
  • S A Bright, A M McElligott, J W O'Connell, L O'Connor, P Carroll, G Campiani, M W Deininger, E Conneally, M Lawler, D C Williams, and D.M Zisterer, Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo , British Journal of Cancer, 102, 2010, p1474 - 1482Journal Article, 2010, DOI , URL , TARA - Full Text
  • Anthony Davies, Anthony McElligott, Graham Pidgeon, Anthony Ryan, Ruth Foley, Cancer Biology where do we go next?, European Pharmaceutical Review, (1), 2010Journal Article, 2010
  • Forde JC., Maginn EN., McNamara G., Martin LM., Campiani GC. , Williams DC, Zisterer D.M, McElligott AM., Lawler M, , Lynch TH, Hollywood D., Marignol L, Microtubule-Targeting-Compound PBOX-15 Radiosensitizes Cancer Cells In Vitro , Cancer Biology and Therapy, 11, (4), 2011, p6 - 13Journal Article, 2011
  • Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gargliardi M, Mc Elligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ, Zisterer DM, The vascular targeting agent Combretastatin-A4 and a novel cis-restricted {beta}-lactam analogue CA-432 induce apoptosis in human chronic myeloid leukemia cells and in ex vivo patient samples including those displaying multidrug resistance., The Journal of Pharmacology and Experimental Therapeutics, 335, (2), 2010, p302 - 313Journal Article, 2010, DOI
  • Maginn EN, Browne PV, Hayden P, Vandenberghe E, McDonagh B, Evans P, Goodyer M, Tewari P, Campiani G, Butini S, Williams DC, Zisterer DM, Lawler MP, McElligott AM., PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells., British Journal of Cancer, 104, (2), 2011, p281 - 289Journal Article, 2011, DOI
  • Langabeer SE, Quinn F, O'Brien D, McElligott AM, Kelly J, Browne PV, Vandenberghe E, Incidence of the BRAF V600E mutation in chronic lymphocytic leukaemia and prolymphocytic leukaemia, Leukemia Research, 36, (4), 2012, p483 - 484Journal Article, 2012
  • Lysaght J, Verma NK, Maginn EN, Ryan JM, Campiani G, Zisterer DM, Williams DC, Browne PV, Lawler MP, McElligott AM., The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells, International Journal of Oncology, 42, (1), 2013, p239 - 249Journal Article, 2013, DOI , TARA - Full Text
  • Langabeer S, O'Brien D, McElligott AM, Lavin M, Browne P, BRAF V600E-negative hairy cell leukaemia, Case Reports in Hematology, 2013Journal Article, 2013, DOI , TARA - Full Text