Professor James O'Donnell

Clinical Senior lecturer, Haematology

[email protected]

Publications and Further Research Outputs

Peer-Reviewed Publications

Tobin WO, Kinsella JA, Kavanagh GF, O'Donnell JS, McGrath RT, Tierney S, Egan B, Feeley TM, Coughlan T, Collins DR, O'Neill D, Murphy SJ, Lim SJ, Murphy RP, McCabe DJH, Profile of von Willebrand factor antigen and von Willebrand factor propeptide in an overall TIA and ischaemic stroke population and amongst subtypes., J Neurol Sci, 375, 2017, p404 - 410Journal Article, 2017, DOI , URL
O'sullivan, J.M. and Preston, R.J.S. and Robson, T. and O'donnell, J.S., Emerging Roles for von Willebrand Factor in Cancer Cell Biology, Seminars in Thrombosis and Hemostasis, 2017Journal Article, 2017, DOI , URL
Gleeson, E.M. and McDonnell, C.J. and Soule, E.E. and Willis Fox, O. and Rushe, H. and Rehill, A. and Smith, O.P. and O'Donnell, J.S. and Preston, R.J.S., A novel proteinC"factorVII chimera provides new insights into the structural requirements for cytoprotective protease-activated receptor1 signaling, Journal of Thrombosis and Haemostasis, 15, (11), 2017, p2198-2207Journal Article, 2017, DOI , URL
Brophy, T.M. and Ward, S.E. and McGimsey, T.R. and Schneppenheim, S. and Drakeford, C. and O'Sullivan, J.M. and Chion, A. and Budde, U. and O'Donnell, J.S., Plasmin cleaves von willebrand factor at K1491-R1492 in the A1-A2 linker region in a shear- and glycan-dependent manner in vitro, Arteriosclerosis, Thrombosis, and Vascular Biology, 37, (5), 2017, p845-855Journal Article, 2017, DOI , URL
Collins, P. and Chalmers, E. and Chowdary, P. and Keeling, D. and Mathias, M. and O'Donnell, J. and Pasi, K.J. and Rangarajan, S. and Thomas, A., The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO, Haemophilia, 22, (4), 2016, p487-498Journal Article, 2016, DOI , URL
O'Sullivan, J.M. and Preston, R.J.S. and O'Regan, N. and O'Donnell, J.S., Emerging roles for hemostatic dysfunction in malaria pathogenesis, Blood, 127, (19), 2016, p2281-2288Journal Article, 2016, DOI , URL
O'Sullivan, J.M. and Jenkins, P.V. and Rawley, O. and Gegenbauer, K. and Chion, A. and Lavin, M. and Byrne, B. and O'Kennedy, R. and Preston, R.J.S. and Brophy, T.M. and O'Donnell, J.S., Galectin-1 and galectin-3 constitute novel-binding partners for Factor VIII, Arteriosclerosis, Thrombosis, and Vascular Biology, 36, (5), 2016, p855-863Journal Article, 2016, DOI , URL
O'regan, N. and Gegenbauer, K. and O'sullivan, J.M. and Maleki, S. and Brophy, T.M. and Dalton, N. and Chion, A. and Fallon, P.G. and Grau, G.E. and Budde, U. and Smith, O.P. and Craig, A.G. and Preston, R.J.S. and O'Donnell, J.S., A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria, Blood, 127, (9), 2016, p1192-1201Journal Article, 2016, DOI , URL
Lavin, M. and O'Donnell, J.S., New treatment approaches to von Willebrand disease, Hematology, 2016, (1), 2016, p683-689Journal Article, 2016, DOI , URL
Quinn, L.M. and Drakeford, C. and O'Donnell, J.S. and Preston, R.J.S., Engineering activated protein C to maximize therapeutic efficacy, Biochemical Society Transactions, 43, 2015, p691-695Journal Article, 2015, DOI , URL
Rawley, O. and O'Sullivan, J.M. and Chion, A. and Keyes, S. and Lavin, M. and van Rooijen, N. and Brophy, T.M. and Fallon, P. and Preston, R.J.S. and O'Donnell, J.S., von Willebrand factor arginine 1205 substitution results in accelerated macrophage-dependent clearance in vivo, Journal of Thrombosis and Haemostasis, 13, (5), 2015, p821-826Journal Article, 2015, DOI , URL
Laffan, M.A. and Lester, W. and O'Donnell, J.S. and Will, A. and Tait, R.C. and Goodeve, A. and Millar, C.M. and Keeling, D.M. and Dolan, G., The diagnosis and management of von Willebrand disease: A United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology, British Journal of Haematology, 167, (4), 2014, p453-465Journal Article, 2014, DOI , URL
Gleeson, E.M. and O'Donnell, J.S. and Hams, E. and inle, F.N. and Kenny, B.-A. and Fallon, P.G. and Preston, R.J.S., Activated factor x signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells, Haematologica, 99, (1), 2014, p185-193Journal Article, 2014, DOI , URL
O'Donnell J, Tuddenham E, Manning R, Kemball-Cook G, and Laffan M. , High prevalence of elevated Factor VIII levels in patients referred for thrombophilia screening: role of increased synthesis and relationship to the acute phase reaction., Thrombosis and Haemostasis, 77, 1997, p825 - 828Journal Article, 1997
O'Donnell J, Roberts I, Daly P, New H and Dokal I., Successful second bone marrow transplant for Fanconi's anaemia following escalation of conditioning., British Journal of Haematology, 98, 1997, p772 - 774Journal Article, 1997
O'Donnell J, Goldman JM, Wagner K, Ehinger G, and Roberts I. , Donor-derived plasmodium vivax infection following volunteer unrelated bone marrow transplantation., Bone Marrow Transplantation, (21), 1998, p313 - 314Journal Article, 1998
O'Donnell J and Laffan M, Factor VIII and thrombosis, CME Bulletin Haematology, 2, 1999, p44 - 46Journal Article, 1999
Mumford A, O'Donnell J, Gillmore J, Manning R, and Laffan M. , Bleeding symptoms and coagulation test abnormalities in 337 patients with AL amyloidosis., British Journal of Haematology, 110, 2000, p454 - 460Journal Article, 2000
O'Donnell J, Mumford AD, Manning RA and Laffan M. , Elevation of FVIII:C in venous thromboembolism is persistent and independent of the acute phase response., Thrombosis and Haemostasis, 83, 2000, p10 - 13Journal Article, 2000
O'Donnell J, Mille-Baker B and Laffan M, Human umbilical vein endothelial cells differ from other endothelial cells in failing to express ABO blood group antigens., Journal of Vascular Research, 37, 2000, p540 - 547Journal Article, 2000
O'Donnell J and Laffan M, Elevated plasma factor VIII:C - a novel independent risk factor for venous thromboembolism. , Clinical Laboratory , 47, 2001, p1 - 6Journal Article, 2001
O'Donnell J, Mumford AD, Manning RA and Laffan MA. , Marked elevation of thrombin generation in patients with elevated FVIII:C and venous thromboembolism., British Journal of Haematology, 115, 2001, p687 - 697Journal Article, 2001
O'Donnell J and Laffan M, The relationship between ABO histo-blood group, factor VIII and von Willebrand factor. , Transfusion Medicine, 11, 2001, p1 - 10Journal Article, 2001
O'Donnell J, Boulton FE, Manning RA, and Laffan M., The amount of H antigen expressed on circulating vWF is modified by ABO blood group genotype and is a major determinant of plasma vWF:Ag levels. , Arteriosclerosis, Thrombosis and Vascular Biology, 22, 2002, p335 - 341Journal Article, 2002
O'Donnell J and Perry DJ., Pharmacotherapy of hyperhomocysteinaemia in patients with thrombophilia., Expert Opinion on Pharmacotherapy, 3, 2002, p1591 - 1598Journal Article, 2002
O'Donnell J, Boulton FE, Manning RA, and Laffan M., Genotype at the Secretor blood group locus is a determinant of plasma von Willebrand factor level., British Journal of Haematology, 116, 2002, p350 - 356Journal Article, 2002
O'Donnell J, Manning RA and Laffan M., The relationship between plasma concentration of a2-macroglobulin and ABO blood group., Thrombosis and Haemostasis, 88, 2002, p167 - 168Journal Article, 2002
Mumford AD, Laffan MA, O'Donnell J, McVey JH, Manning RA, and Kemball-Cook G., A Tyr346Cys substitution in the inter-domain acidic region a1 of Factor VIII in an individual with Factor VIII:C assay discrepancy. , British Journal of Haematology, 118, 2002, p589 - 594Journal Article, 2002
Doyle S, O'Brien P, Murphy K, and O'Donnell J. , Coagulation factor content of solvent / detergent plasma compared to fresh frozen plasma., Blood Coagulation and Fibrinolysis, 14, 2003, p283 - 287Journal Article, 2003
O'Donnell J, and Laffan M. , Dissociation of ABH antigen expression from von Willebrand factor synthesis in endothelial cell lines., British Journal of Haematology , 121, 2003, p928 - 931Journal Article, 2003
O'Brien P, Murphy K, and O'Donnell J. , Acquired protein S deficiency in TTP patients receiving solvent / detergent plasma exchange. , British Journal of Haematology, 122, 2003, p518 - 519Journal Article, 2003
O'Donnell J, Manning RA, and Laffan M., Beta-adrenergic receptor polymorphisms in patients with elevated FVIII levels with venous thrombosis., British Journal of Haematology, 123, 2003, p139 - 141Journal Article, 2003
O'Donnell J, Riddell A, Owens D, Pasi KJ and Perry DJ., Role of the Thromboelastograph as an adjunctive test in thrombophilia screening., Blood Coagulation and Fibrinolysis , 15, 2004, p207 - 211Journal Article, 2004
O'Connell MP, Murphy KM, White B and O'Donnell J., Solvent-detergent plasma as replacement therapy in a pregnant patient with factor V deficiency., Journal of Maternal Fetal and Neonatal Medicine, 16, 2004, p69 - 70Journal Article, 2004
Baguley C, Guri S, O'Donnell J, and Howard D., Consumptive coagulopathy complicating juvenile angiofibroma. , Journal of Laryngology and Otology,, 118, 2004, p835 - 839Journal Article, 2004
Crawley JTB, Lam JK, Rance JB, Mollica LR, O'Donnell JS and Lane DA., Proteolytic Regulation of ADAMTS-13: Novel Roles for Thrombin and Plasmin., Blood, 105, 2005, p1085 - 1093Journal Article, 2005
O'Donnell J. , Prevention of hospital acquired venous thromboembolism., British Medical Journal Learning., 1, 2005, p1 - 5Journal Article, 2005
O'Donnell JS., Severe factor V deficiency and pregnancy - a role for solvent-detergent plasma? , Haemophilia, 11, 2005, p422 - 423Journal Article, 2005
Cunningham N, Laffan MA, Manning RA and O'Donnell J. , Role of Low-Density Lipoprotein Receptor-Related Protein (LRP) in Patients with Elevated FVIII:C and Venous Thrombosis., Blood Coagulation and Fibrinolysis, , 16, 2005, p465 - 468Journal Article, 2005
O'Donnell JS, McKinnon TAJ, Crawley JTB, Lane DA and Laffan MA., Bombay phenotype is associated with reduced plasma VWF levels and an increased susceptibility to ADAMTS13 proteolysis., Blood, 106, 2005, p1988 - 1991Journal Article, 2005
Cunningham SE, White B, and O'Donnell JS., Prevention and management of venous thrombo-embolism in patients with cancer - a review of the evidence., Clinical Oncology, 1, 2006, p145 - 151Journal Article, 2006
Cunningham SE, White B, Hollywood D, and O'Donnell JS., Primary thromboprophylaxis for cancer patients with central venous catheters - a reappraisal of the evidence., British Journal of Cancer, 94, 2006, p189 - 194Journal Article, 2006
O'Donnell JS, Hinkson L, McCarthy A, Manning R, Khan A, and Lafffan MA, Antithrombin Nagasaki (Ser 116 to Pro): a rare antithrombin variant with abnormal heparin binding presenting during pregnancy., Blood Coagulation and Fibrinolysis, 17, 2006, p217 - 220Journal Article, 2006
Hollestelle MKJ, Donkor C, Mantey E, Craig A, Akoto J, O'Donnell J, van Mourik J, Bunn J. , Von Willebrand factor propeptide in severe malaria: evidence of acute endothelial cell activation. , British Journal of Haematology, 133, 2006, p562 - 569Journal Article, 2006
Jenkins PV and O'Donnell JS., ABO blood group determines plasma von Willebrand factor levels - a biological function after all?, Transfusion, 46, 2006, p1836 - 1844Journal Article, 2006
Loscertales MP, Owens S, O'Donnell JS, Bunn J, Brabin BJ., ABO blood group phenotypes and falciparum malaria: unlocking a pivotal mechanism., Advances in Parasitology, 65, 2007, p1 - 50Journal Article, 2007
Winter PC, Egan H, McNulty O, Jones FG, O'Donnell J, Jenkins PV, Recurrent F8 Mutation in Irish Haemophilia A Patients: Evidence for a Founder Effect., Haemophilia, 14, 2008, p394 - 395Journal Article, 2008
Hochart H, Jenkins PV, Preston RJ, Smith OP, White B, O'Donnell JS, Concentration-dependent roles for heparin in modifying LPS-induced activation of mononuclear cells in whole blood., Thrombosis and Haemostasis, 99, 2008, p570 - 575Journal Article, 2008
Jenkins PV, Egan H, Keenan C, Mellars G; O'Shea E, Nolan B, White B, O'Donnell J., Factor IX mutations and Haemophilia B in the Irish Population: Distinct genetic mechanisms for severe and mild haemophilia B., Haemophilia , 14, 2008, p717 - 722Journal Article, 2008
N inle F, Wong A, Appleby N, Byrne B, O Sullivan A, White B, O'Donnell J. , Efficacy and safety of once daily low molecular weight heparin (Tinzaparin sodium) in high risk pregnancy., Blood Coagulation and Fibrinolysis,, 19, 2008, p689 - 692Journal Article, 2008
Cunningham SM, Gilmore R, O'Donnell D, O'Donnell JS., Management of refractory venous thrombosis associated with malignancy using a supra-therapeutic Enoxaparin regimen. , Irish Journal of Medical Science,, 1, 2008, pe1 - e3Journal Article, 2008
Gilmore R, Doyle M, Holden F and O'Donnell J, Activated protein C resistance, factor V Leiden and assessment of thrombotic risk, Irish Medical Journal, 101, (8), 2008, p256 - 257Journal Article, 2008
Preston, RJ, Tran, S, Johnson, JA, Ainle, FN, Harmon, S, White, B, Smith, OP, Jenkins, PV, Dahlbck, B, O'Donnell, JS, Platelet factor 4 impairs the anticoagulant activity of activated protein C., The Journal of Biological Chemistry, 284, (9), 2009, p5869 - 5875Journal Article, 2009, DOI , URL , TARA - Full Text
Harmon, S, Preston, RJ, Ainle, FN, Johnson, JA, Cunningham, MS, Smith, OP, White, B, O'Donnell, JS, Dissociation of activated protein C functions by elimination of protein S cofactor enhancement., The Journal of Biological Chemistry, 283, (45), 2008, p30531 - 30539Journal Article, 2008, DOI , URL , TARA - Full Text
Larkin, D, de Laat, B, Jenkins, PV, Bunn, J, Craig, AG, Terraube, V, Preston, RJ, Donkor, C, Grau, GE, van Mourik, JA, O'Donnell, JS, Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition., PLoS Pathogens, 5, (3), 2009, p1 - 8Journal Article, 2009, DOI , URL , TARA - Full Text
Preston RJ, Morse, Cutler, Murden, Brady SK, O'Donnell JS, Mumford AD. , Pseudo-homozygous protein C deficiency due to co-inheritance of novel type I and type IIb protein C variants., British Journal of Haematology, 144, (6), 2009, p946 - 953Journal Article, 2009
Cunningham MS, Preston RJ, and O'Donnell JS. , Does antithrombotic therapy improve survival in cancer patients?, Blood Reviews, 23, 2009, p129 - 135Journal Article, 2009
Gilmore R, Harmon S, Keane G, Gannon C and O'Donnell JS , Variation in anticoagulant composition regulates differential effects of prothrombin complex concentrates on TF-initiated thrombin generation, Journal Thrombosis Haemostasis, 7, (12), 2009, p2154 - 2156Journal Article, 2009
Ni Ainle F, Preston RJ, Jenkins PV, Johnson JS, Nell H, Fallon PG, White B, O'Donnell JS. , Protamine sulphate downregulates thrombin generation by inhibiting factor V activation, Blood, 114, (8), 2009, p1658 - 1665Journal Article, 2009
Terraube V, O'Donnell JS, Jenkins PV, Factor VIII and von Willebrand interactions - biochemical basis and physiological significance, Haemophilia, 16, (1), 2010, p3 - 13Journal Article, 2010
Sherlock E, O'Donnell JS, White B, Blake C , Physical activity levels and participation in sport in Irish people with haemophilia, Haemophilia, 16, (1), 2010, pe202 - e209Journal Article, 2010
Bridges DJ, Bunn J, van Mourik J, Preston RJ, Molyneux M, Combes V, O'Donnell JS, de Laat B, Craig A. , Rapid activation of endothelial cells enables P. falciparum adhesion to platelet decorated von Willebrand factor strings, Blood, 115, (7), 2010, p1472 - 1474Journal Article, 2010
Byrne M, Reynolds JV, O'Donnell JS, Keogan M, White B, Murphy S, Maher S, Pidgeon G, Activation of the procoagulant response following neoadjuvant chemotherapy and radiation therapy, and long-term activation following major cancer surgery, British Journal of Cancer, 102, (1), 2010, p73 - 79Journal Article, 2010
McLean S, Ryan M, O'Donnell JS, Role of primary thromboprophylaxis in the palliative care setting - a systematic review, Palliative Medicine, 24, (4), 2010, p386 - 395Journal Article, 2010
Harris L, Castro-Lpez V, Hammadi N, O'Donnell JS, Killard AJ, The development of a fluorescent anti-factor Xa (FXa) assay and its application to the monitoring of a range of heparin-like anticoagulants, Talanta, 81, (4-5), 2010, p1725 - 1730Journal Article, 2010
McGrath R, McKinnon TA, Byrne B, O'Kennedy R, McRae E, Preston RJ, O'Donnell JS, Terminal 2-6 linked sialic acid expression determines VWF proteolysis by ADAMTS13, Blood, 115, (13), 2010, p2666 - 2673Journal Article, 2010
McGrath R, McRae E, Smith OP, O'Donnell JS, Platelet VWF - structure, function and biological significance, British Journal of Haematology, 148, (6), 2010, p834 - 843Journal Article, 2010
Gilmore R, Harmon S, Gannon C, O'Donnell JS, Jenkins PV, Thrombin generation in haemophilia A patients with factor VIII assay discrepancy, Haemophilia, 16, (4), 2010, p671 - 674Journal Article, 2010
Castro-Lopez V, Harris LF, O'Donnell JS and Killard AJ, Comparative study of Factor Xa fluorogenic substrates and their influence on the quantification of LMWHs, Analytical and Bioanalytical Chemistry, 399, 2011, p691 - 700Journal Article, 2011
Cumming AM, Keeney S, Jenkins PV, Nash MJ, O'Donnell JS, Clinical utility gene card for: von Willebrand disease, European Journal of Human Genetics, Jan 5, 2011, pEpub-Journal Article, 2011
Ni Ainle F*, O'Donnell JS* (joint first author), Johnson J, Gleeson E, Smith OP, Preston RJ. , Activated protein C N-linked glycans regulate cytoprotective signalling on endothelial cells, Journal of Biological Chemistry, 286, (2), 2011, p1323 - 1330Journal Article, 2011
Vanessa Castro-Lopez, Leanne F. Harris, James S. O'Donnell, Anthony J. Killard, Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays, Journal of Pharmaceutical and Biomedical Analysis, 56, (5), 2011, p992-997Journal Article, 2011, DOI , URL , TARA - Full Text
Castro-Lpez V, Murray B, Harris LF, O'Donnell JS, Killard AJ, Effects of four commercially available factor Xa proteins on the fluorogenic anti-factor Xa assay when monitoring unfractionated heparin., Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis, 2011Journal Article, 2011, DOI , URL
Tobin WO, Kinsella JA, Kavanagh GF, O'Donnell JS, McGrath RA, Collins DR, Coughlan T, O'Neill D, Egan B, Tierney S, Feeley TM, Murphy RP, McCabe DJ, Longitudinal assessment of thrombin generation potential in response to alteration of antiplatelet therapy after TIA or ischaemic stroke., Journal of Neurology, 260, (2), 2013, p590-6Journal Article, 2013, DOI
Preston RJ, Rawley O, Gleeson EM, O'Donnell JS, Elucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunities., Blood, 121, (19), 2013, p3801 - 3810Journal Article, 2013
McGrath RT, van den Biggelaar M, Byrne B, O'Sullivan JM, Rawley O, O'Kennedy R, Voorberg J, Preston RJ, O'Donnell JS. , Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis. , Blood, 122, (25), 2013, p4107 - 4110Journal Article, 2013
Kinsella JA, Tobin WO, Kavanagh GF, O'Donnell JS, McGrath RT, Tierney S, Feeley TM, Egan B, O'Neill D, Collins RD, Coughlan T, Harbison JA, Doherty CP, Madhavan P, Moore DJ, O'Neill SM, Colgan MP, Saqqur M, Murphy RP, Moran N, Hamilton G, McCabe DJ, Increased endothelial activation in recently symptomatic versus asymptomatic carotid artery stenosis and in cerebral microembolic-signal-negative patient subgroups., European Journal of Neurology, 2014, p460-467Journal Article, 2014, DOI , TARA - Full Text
Kinsella JA, Tobin WO, Kavanagh GF, O'Donnell JS, McGrath RT, Tierney S, Feeley TM, Egan B, O'Neill D, Collins DR, Coughlan T, Harbison JA, Doherty CP, Madhavan P, Moore DJ, O'Neill SM, Colgan MP, Saqqur M, Murphy RP, Moran N, Hamilton G, McCabe DJ, Increased thrombin generation potential in symptomatic versus asymptomatic moderate or severe carotid stenosis and relationship with cerebral microemboli., Journal of Neurology, Neurosurgery, and Psychiatry, 86, 2015, p460-467Journal Article, 2015, DOI
Bacon CL, Singleton E, Brady B, White B, Nolan B, Gilmore R, O'Donnell JS. , Low risk of inhibitor formation in haemophilia A patients following an en masse switch in treatment to a third generation full length recombinant FVIII product. , Haemophilia, 17, (3), 2011, p407 - 411Journal Article, 2011
Keeney S, Cumming AM, Nash MJ, O'Donnell JS, Jenkins PV. , Clinical utility gene card for: Haemophilia A., European Journal of Human Genetics,, 19, (11), 2011, p107 - 111Journal Article, 2011
Harris LF, O'Brien A, Castro-Lpez V, O'Donnell JS, Killard AJ. , Comparison of the anticoagulant response of a novel fluorogenic anti-FXa assay with two commercial anti-FXa chromogenic assays., Thrombosis Research, , 128, (6), 2011, p125 - 129Journal Article, 2011
Harris LF, Castro-Lpez V, Jenkins PV, O'Donnell JS, Killard AJ. , Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas., Thrombosis Research, 128, (6), 2011, p166 - 170Journal Article, 2011
Harris LF, Castro-Lpez V, Jenkins PV, O'Donnell JS, Killard AJ. , Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas., Thrombosis Research, 128, (6), 2011, p166 - 170Journal Article, 2011
Gleason EM, O'Donnell JS, Preston RJ. , The Endothelial Cell Protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling. , Cellular and Molecular Life Sciences, 69, (5), 2012, p717 - 726Journal Article, 2012
Ryan K, O'Donnell JS, Elevated plasma factor VIII levels in patients with venous thrombosis - Constitutional risk factor or secondary epiphenomenon?, Thrombosis Research, 129, (2), 2012, p105 - 106Journal Article, 2012
Jenkins PV, Keenan C, Keeney S, Cumming T, O'Donnell JS, Clinical utility gene card for: haemophilia B., European Journal of Human Genetics, 20, (5), 2012, p268 - 271Journal Article, 2012
Jenkins PV, Rawley O, Smith OP, O'Donnell JS, Elevated factor VIII levels and risk of venous thromboembolism., British Journal of Haematology, 157, (6), 2012, p653 - 663Journal Article, 2012
O'Donnell D, O'Connell N, O'Donnell JS, Einstein-PE study should not affect VTE therapy for cancer patients., New England Journal of Medicine, 366, (26), 2012, p2525-Journal Article, 2012
Berntorp E, Fuchs B, Makris M, Montgomery RR, Flood VH, O'Donnell JS, Federici A, Lillicrap D, James P, Budde U, Morfini M, Petrini P, Austin S, Kannicht C, Lee C. , Third land island conference on von Willebrand disease, Haemophilia, (Supp 3), 2013, p1 - 18Journal Article, 2013
Tilley DO, Albert MA, Smolenski A, Cox D, O'Donnell JS, Douglas CW, Watson SP, Kerrigan SW., Glycoprotein Ib and FcRIIa play key roles in platelet activation by the colonizing bacterium, Streptococcus oralis, Journal of Thrombosis and Haemostasis, 11, (5), 2013, p941 - 950Journal Article, 2013
Harris LF, Rainey P, Castro-Lpez V, O'Donnell JS, Killard AJ. , A microfluidic anti-Factor Xa assay device for point-of-care monitoring of anticoagulation therapy. , Analyst, 138, (17), 2013, p4769 - 4776Journal Article, 2013
Gleason E, O'Donnell JS, Hams E, Fallon PF, Preston RJ. , Activated Factor X Inhibits Leukocyte Pro-inflammatory Cytokine Release upon Toll-like Receptor Stimulation. , Haematologica, 99, (1), 2014, p185 - 193Journal Article, 2014
Matino D, Lillicrap D, Astermark J, Dolan G, Kessler C, Lambert T, Makris M, O'Donnell JS, Pipe S, Santagostino E, Saint-Remy, Iorio A., Switching clotting factor concentrates: Considerations in estimating the risk of immunogenicity., Haemophilia, 20, (2), 2014, p200 - 206Journal Article, 2014
Tobin WO, Kinsella JA, Kavanagh GF, O'Donnell JS, McGrath RT, Tierney S, Egan B, Feeley TM, Coughlan T, Collins DR, Harbison JA, McCabe DJH, Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke., Journal of Neurology, 261, (7), 2014, p1405 - 1412Journal Article, 2014
Laffan M, Lester W, O'Donnell JS, Will A, Tait RC, Goodeve A, Millar CM, Keeling D , Diagnosis and management of von Willebrand disease: A United Kingdom Haemophilia Centre Doctors Organisation guideline approved by the British Committee for Standards in Haematology., British Journal of Haematology, 2014Journal Article, 2014