Publications and Further Research Outputs
- Brady G, Haas DA, Farrell PJ, Pichlmair A, Bowie AG, Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-B Activation by Targeting p65 for Degradation., Journal of virology, 89, (16), 2015, p8406-15Journal Article, 2015, DOI , TARA - Full Text
- Brady, G., Haas, D.A., Farrell, P.F., Pichlmair, A. and Bowie, A.G. , Molluscum Contagiosum Virus protein MC005 inhibits NFκB activation by targeting NEMO-regulated IKK activation, The Journal of Virology, 91, (15), 2017, p00545-17Journal Article, 2017, DOI , TARA - Full Text
- Brady G, Boggan L, Bowie A, O'Neill L.A.J, Erratum: Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1 (The Journal of Biological Chemistry (2005) 280 (30723-30734) DOI: 10.1074/jbc.M500435200), Journal of Biological Chemistry, 291, (48), 2016, p25278-Journal Article, 2016, DOI , URL
- Fitzgerald, K. A., Palsson-McDermott, E. M., Bowie, A. G., Jefferies, C. A., Mansell, A. S., Brady, G., Brint, E., Dunne, A., Gray, P., Harte, M. T., McMurray, D., Smith, D. E., Sims, J. E., Bird, T. A., and O'Neill, L. A., Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413, 78-83, Nature, 413, 2001, p73 - 83Journal Article, 2001
- Lucchesi, W., Brady, G., Dittrich-Breiholz, O., Kracht, M., Russ, R., and Farrell, P. J., Differential gene regulation by Epstein-Barr virus type 1 and type 2 EBNA2. , Journal of virology, 82, 2008, p7456 - 7466Journal Article, 2008
- Brady, G., Whiteman, H. J., Spender, L. C., and Farrell, P. J., Downregulation of RUNX1 by RUNX3 requires the RUNX3 VWRPY sequence and is essential for Epstein-Barr virus-driven B-cell proliferation., Journal of Virology, 83, 2009, p6909 - 6916Journal Article, 2009
- Brady, G., and Farrell, P. J., RUNX3-mediated repression of RUNX1 in B cells. , Journal of cellular physiology , 221, 2009, p283-2Review Article, 2009
- Brady, G., MacArthur, G. J., and Farrell, P. J., Epstein-Barr virus and Burkitt lymphoma., J Clin Pathol., 60(12):13, 2007, p1397-402Review Article, 2007
- Brady G, C.E. Karstegl and P.J. Farrell, Novel function of the unique N terminal region of RUNX1c in B cell growth regulation, Nucleic Acids Research, Feb 1;41(3), 2013, p1555-68Journal Article, 2013
- Brady G and Bowie AG , Poxviral inhibitors of NFκB, Cytokine and Growth Factor Reviews, Oct;25(5), 2014, p611-2Review Article, 2014
- Brady G, Hass DA, Pichlmair A, Farrell PJ, and Bowie AG. , Human Poxvirus protein MC132 from Molluscum Contagiosum Virus inhibits NFκB activation by targeting p65 for degradation., Journal of Virology , (89), 2015, p8406-15Journal Article, 2015, DOI , TARA - Full Text
- Dearbhaile Dooley, Mirjan M. van Timmeren, Vincent P. O'Reilly, Gareth Brady, Eoin C. O'Brien, Barbara Fazekas, Fionnuala B. Hickey, Emma Leacy, Charles D. Pusey, Frederick W.K. Tam, Thomas Mehrling, Peter Heeringa and Mark A. Little, Alkylating histone deacetylase inhibitors may have therapeutic value in experimental myeloperoxidase-ANCA vasculitis, Kidney International, 94, (5), 2018, p926 - 993Journal Article, 2018, DOI , TARA - Full Text
- C. Jefferies, A. Bowie, G. Brady, E. L. Cooke, X. Li and L. A. O'Neill, Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1, Molecular and cellular biology, 21, (14), 2001, p4544-52Journal Article, 2001, URL , TARA - Full Text
- Phelan T, Little MA, Brady G., Targeting of the cGAS-STING system by DNA viruses., Biochemical Pharmacology, 174:113831, 2020Journal Article, 2020, URL
- Ui Mhaonaigh, A., Coughlan, A. M., Dwivedi, A., Hartnett, J., Cabral, J., Moran, B., Brennan, K., Doyle, S. L., Hughes, K., Lucey, R., Floudas, A., Fearon, U., McGrath, S., Cormican, S., De Bhailis, A., Molloy, E. J., Brady, G., & Little, M. A., Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies., Frontiers in immunology, 10, (2603), 2019Journal Article, 2019, DOI , TARA - Full Text
- Lawler C, Brady G. , Poxviral Targeting of Interferon Regulatory Factor Activation. , Viruses, 12, (10), 2020Journal Article, 2020, DOI , TARA - Full Text
- David Casserly, Lili Gu, Gareth Brady, Susan Carpenter, Adrian P. Bracken, Katherine A Fitzgerald, Leonie Unterholzner, and Andrew G Bowie., MNDA controls the pathogen-stimulated type I IFN cascade in human monocytes by transcriptional regulation of IRF7., Nature Communications, 2020Journal Article, 2020
- Leacy E, Brady G, Little MA., Pathogenesis of ANCA-associated vasculitis: an emerging role for immunometabolism., Rheumatology, 59, (Supplement 3), 2020Journal Article, 2020, DOI
- Dyer AH, Noonan C, McElheron M, Batten I, Reddy C, Connolly E, Pierpoint R, Murray C, Leonard A, Higgins C, Reilly P, Boran G, Phelan T, McCormack W, O'Neill D, Fallon A, Brady G, O'Farrelly C, Bourke NM, Kennelly SP., Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents, Journal of the American Medical Directors Association, 2022Journal Article, 2022, DOI , URL
- Gu L, Casserly D, Brady G, Carpenter S, Bracken AP, Fitzgerald KA, Unterholzner L, Bowie AG., Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7., Nature communications, 13, (1), 2022, p14Journal Article, 2022, DOI , TARA - Full Text
- AL Hamrashdi, M. and Brady, G., Regulation of IRF3 activation in human antiviral signaling pathways, Biochemical Pharmacology, 200, (115026), 2022Journal Article, 2022, DOI , URL
- Phelan, T. and Dunne, J. and Conlon, N. and Cheallaigh, C.N. and Abbott, W.M. and Faba-Rodriguez, R. and Amanat, F. and Krammer, F. and Little, M.A. and Hughes, G. and Bergin, C. and Kerr, C. and Sundaresan, S. and Long, A. and McCormack, W. and Brady, G., Article dynamic assay for profiling anti-sars-cov-2 antibodies and their ace2/spike rbd neutralization capacity, Viruses, 13, (7), 2021Journal Article, 2021, DOI , URL
- Maguire, F. and Murphy, M.E. and Rourke, M. and Morgan, F. and Brady, G. and Byrne, E. and O Callaghan, M.E., A cross-sectional study of antibiotic prescribing for childhood upper respiratory tract infections in irish general practice, Irish Medical Journal, 111, (10), 2018, p835Journal Article, 2018, URL
- Brady G, Boggan L, Bowie A and O'Neill LA, Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1, Journal of Biological Chemistry, 280, (35), 2005, p30723 - 30734Journal Article, 2005, DOI , TARA - Full Text
- Gubster C, Goodbody R, Ecker A, Brady G, O'Neill LA, Jacobs N, Smith GL., Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus, Journal of General Virology, 88, (6), 2007, p1667-1676Journal Article, 2007, DOI , TARA - Full Text
- Brady, Gareth Bowie, Andrew G., Innate immune activation of NFκB and its antagonism by poxviruses, Cytokine & Growth Factor Reviews, 2014Journal Article, 2014, DOI , TARA - Full Text
- Brady, G., Macarthur, G. J., and Farrell, P. J., Epstein-Barr virus and Burkitt lymphoma. , Postgraduate medical Journal, 84, 2008, p372-377Review Article